ER-Tracker Green
CAS No. 730931-46-1
ER-Tracker Green ( —— )
产品货号. M35231 CAS No. 730931-46-1
ER-Tracker 染料是与 Glibenclamide (HY-15206) 偶联的 BODIPY 列染料的衍生物,对内质网高选择性结合,在低浓度下对细胞无毒性,该类染料属于环境敏感型的探针,与甲醛处理后仍能保留部分荧光,具有荧光寿命高,消光系数好等特点。Glibenclamide 是一种 ATP 依赖性 K+ 通道阻滞剂 (Kir6, KATP) 和 CFTR Cl-通道阻滞剂,在内质网中发生结合。ER-Tracker 不适合对固定后细胞进行染色。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥1499 | 有现货 |
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| 5MG | ¥2334 | 有现货 |
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| 10MG | ¥3860 | 有现货 |
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| 25MG | ¥7468 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称ER-Tracker Green
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述ER-Tracker 染料是与 Glibenclamide (HY-15206) 偶联的 BODIPY 列染料的衍生物,对内质网高选择性结合,在低浓度下对细胞无毒性,该类染料属于环境敏感型的探针,与甲醛处理后仍能保留部分荧光,具有荧光寿命高,消光系数好等特点。Glibenclamide 是一种 ATP 依赖性 K+ 通道阻滞剂 (Kir6, KATP) 和 CFTR Cl-通道阻滞剂,在内质网中发生结合。ER-Tracker 不适合对固定后细胞进行染色。
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产品描述ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation.
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体外实验——
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域——
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适应症——
化学信息
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CAS Number730931-46-1
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分子量783.09
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分子式C37H42BClF2N6O6S
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO 中的溶解度 : 50 mg/mL (63.85 mM; 超声助溶 )
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SMILESCOc1c(NC(=O)CCc2ccc3C=C4C(C)=CC(C)=[N+]4[B-](F)(F)n23)cc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Tanuja T Merianda, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40(2):128-42.?
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